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1-androstene-3beta, 17beta-diol aka 1-AD

$99.99  $49.99
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  • Model: 1-AD
  • Shipping Weight: 0.25lbs
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1-AD Was The ultimate Andro - This is the original chemical which was known as 1-AD

We did it again.  We found a lab that made a small batch of 1-AD, 100 mg, 60 capsule bottles.  We have it and you will not find it anywhere else.

What is 1-AD?

New & Improved "diol" Version. This is without a doubt the strongest andro ever introduced .

A Natural Hormone Made in the Body - One of the beautiful things about 1-AD is that in addition to its impressive pharmacological activity, it is also a natural androgen made in the human body.  Furthermore, 1-AD’s high rate of active conversion after oral administration is not just a “theory” – it has been demonstrated and published in a highly reputable peer reviewed journal.

The future of andro is here, 1-AD. This, without a doubt the single most amazing andro to be synthesized and sold .

Organic chemist Patrick Arnold, was the person who discovered androtenedione and introduced it to the market in 1996. Patrick wanted this andro, 1-AD to have all the attributes most critical to the perfect andro. It had to be:

  • Orally Active
  • Completely Non-Aromatizable to Estrogens
  • Extremely potent
  • Naturally occurring
  • Non-toxic

After months of scouring every book and journal that he could locate, including those in foreign languages (i.e. German), he discovered a compound that seemed to be the perfect candidate. That was the easy part. It then took Patrick almost one whole year to figure out how to manufacture the compound cheaply enough for sale as a supplement. Patrick’s lab took on the appearance of ground zero at Hiroshima as he endlessly did reaction after reaction in pursuit of the perfect manufacturing recipe.

Introducing 1-AD - It’s time to introduce what Patrick refers to as “the crown achievement” of his career.  We nicknamed this compound “1-AD” which is a shortened acronym of its chemical name.

This compound is truly unique amongst other andro in a variety of ways. Let’s look specifically at 1-AD and what it does.

The Power of 1-Testosterone- You probably are familiar with the “Andro” andro, and the “Norandro” andro. 1-AD, however, does not fit into either of those categories. That is because 1-AD converts to a relatively unheard of hormone called 1-testosterone. 1-testosterone is what is known as a “double bond isomer” of testosterone.

Although chemically the only difference between testosterone and 1-testosterone is the position of the double bond, pharmacologically the two products are quite different. According to research done by the pharmaceutical giant G.D. Searle and published in the 1960s, 1-testosterone is over 7 times as myotrophic (anabolic) as testosterone(1). That makes 1-testosterone a phenomenally potent compound, surpassing even most synthetics.

No Aromatization - 1-testosterone differs from testosterone in another way as well. Being a 5alpha-reduced androgen (a DHT derivative) it simply cannot aromatize to estrogens. The same goes for 1-AD itself — no estrogen transformation can occur. This makes 1-AD unique compared to other andro — all of which can either aromatize directly, convert to a product that aromatizes, or both. So what does this mean in the real world? It means that your chances of getting gynecomastia (bitch tits) from 1-AD is essentially zero, and that water retention side effects are vastly reduced compared to other andro.

The Only Truly “Orally Active” Prohormone- Natural androgenic steroids are normally not very active orally. Large amounts have to be taken orally to see biological effects. This is because the first pass through the liver causes a massive deactivation of the compounds, primarily through the oxidation of the 17beta-hydroxyl to a 17-keto group. Chemists long ago found that by adding an alkyl (methyl or ethyl) chemical group to the alpha position of the 17 carbon, this oxidation can be prevented. However, this alkyl derivatization also greatly increases the liver toxicity. Therefore the usage of such synthetically altered compounds (methyltestosterone, oxymetholone, stanozolol) are not without substantial risk.

Luckily, there are other ways to render a steroid orally active, and do so without making the compound toxic to the liver. Certain structural modifications can alter the metabolism of steroids making them resistant to liver breakdown. One of these modifications is unsaturation (presence of a double bond) in the 1-position. One steroid that has this structural modification and is orally active is the anabolic Methenolone, also known as Primobolan.

As you may have noticed, this double bond position that makes Primobolan orally active is the same one found in 1-AD, which, by the way, is also orally active. Steroids with this particular double bond characteristic are known as 1-dehydroandrotanes.

During the 60’s and 70’s some papers were published describing the phenomenon of oral activity seen with 1-dehydroandrotanes, including 1-testosterone and 1-AD. What was discovered was that these compounds resist metabolic deactivation by profoundly shifting what is known as the “17-keto redox potential” towards the formation of active 17beta-hydroxyl steroids(2,3). What does this mean? It means that when you take 1-AD, the liver serves primarily to activate the compound, rather than break it down and excrete it as it does with other andro and testosterone. It means that 1-AD is “orally active,” yet it does not impart the liver toxicity that 17alpha-alkylation does.

A Natural Hormone Made in the Body- One of the beautiful things about 1-AD is that in addition to its impressive pharmacological activity, it is also a natural androgen made in the human body(4). This means that it is not foreign to your body, and that it can legally and openly be sold as a nutritional supplement. Furthermore, 1-AD’s high rate of active conversion after oral administration is not just a “theory” of ErgoPharm’s – it has been demonstrated and published in a highly reputable peer reviewed journal.

Put all together, 1-AD offers:

  • High oral activity
  • Conversion to a hormone 700% more potent than testosterone
  • Absolutely NO aromatization to estrogens
  • Natural and safe.

There can be no argument that this is the ultimate andro. Believe us, there simply are no natural compounds out there that can come close to what 1-AD does, so don’t even bother looking.

Is there any reason not to take 1-AD? Do not take if you have liver dysfunction, or are taking other medications that can affect liver function (ask your physician). May affect fertility in males with prolonged usage. Consult with your physician before using this product. Do not take this product if you have prostate hypertrophy. Not recommended for women or persons under the age of 18. KEEP OUT OF THE REACH OF CHILDREN.

How to use 1-AD: As a dietary supplement, take 1 to 2 capsules up to 3 times per day in divided doses with food. Do not break open capsules. Do not exceed 3 capsules per day. Approximately after three weeks of using 1-AD, the body begins to acknowledge the additional hormone levels and reacts by 'suppressing' the endogenous testosterone levels. What this means is that whatever the body was producing in it's 'natural state'.

Therefore, at this interval in research of all these new precursors and andro supplements, we do suggest short 'cycle' stacking of perhaps three weeks 'on' and three weeks 'off'. This will safely keep the body from becoming 'adapted' to ANY exogenous supplement regime, but at the same time, boost the 'natural' levels as much as possible!

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.


This product was added to our catalog on Thursday 09 November, 2006.

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